New insights on gastro-oesophageal reflux in cystic fibrosis by longitudinal follow up.
نویسندگان
چکیده
A higher frequency (25%) of gastrooesophageal reflux (GOR) has been previously reported in patients over 5 years old with cystic fibrosis compared with controls without cystic fibrosis. It was believed that GOR was caused by the complications of cystic fibrosis. We looked for GOR in all 26 children younger than 60 months who had cystic fibrosis diagnosed. They had a classical genetic profile and the usual scattered clinical manifestations for age. GOR was confirmed in 21 (81%): 20 by abnormal pH tracings and in one on a clinical basis. After at least one month of adjusted cystic fibrosis treatment, antireflux treatment (cisapride) was given to 16 patients and variables of GOR improved dramatically. Weight gain was significant and recurrent cough and wheeze disappeared. One year later half of the patients still suffered from GOR. GOR is a major problem in the early life of those with cystic fibrosis and is not the consequence of either respiratory or gastrointestinal complications as it improves with age whereas cystic fibrosis becomes worse with age.
منابع مشابه
Postural drainage and gastro-oesophageal reflux in infants with cystic fibrosis.
UNLABELLED Gastro-oesophageal reflux is increased in cystic fibrosis and it is possible that postural drainage techniques may exacerbate reflux, potentially resulting in aspiration and further impairment of pulmonary function. AIM To evaluate the effects of physiotherapy with head down tilt (standard physiotherapy, SPT) on gastroesophageal reflux and to compare this with physiotherapy without...
متن کاملPostural drainage techniques and gastro-oesophageal reflux in infants with cystic fibrosis.
متن کامل
Chest physiotherapy, gastro-oesophageal reflux, and arousal in infants with cystic fibrosis.
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عنوان ژورنال:
- Archives of disease in childhood
دوره 66 11 شماره
صفحات -
تاریخ انتشار 1991